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Antioxidant

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Monrroy, M., Araúz, O., & García, J. R. (2020). Active compound identification in extracts of N. lappaceum peel and evaluation of antioxidant capacity. Journal of Chemistry, 2020.
Thitilertdecha, N., Teerawutgulrag, A., Kilburn, J. D., & Rakariyatham, N. (2010). Identification of major phenolic compounds from Nephelium lappaceum L. and their antioxidant activities. Molecules, 15(3), 1453-1465.
Wanlapa S et al. Potential of Selected Tropical Fruit Peels as Dietary Fiber in Functional Foods. International Journal of Food Properties, 18:6, 1306-1316, DOI: 10.1080/10942912.2010.535187
Yongliang Z et al. Purification and identification of rambutan (Nephelium lappaceum) peel phenolics with evaluation of antioxidant and antiglycation activities in vitro. Int J Food Sci & Tech. 2017. Vol 52, Issue 8
Zhuang Y et al. Effects of Rambutan Peel (Nepheliumlappaceum) PhenolicExtract on RANKL-Induced Differentiation of RAW264.7 Cells into Osteoclasts and Retinoic Acid-Induced Osteoporosis in Rats. Nutrients 2020, 12, 883; doi:10.3390/nu12040883

Metabolic Health

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Chung APYS et al. Ellagitannin geraniin supplementation ameliorates metabolic risks in high-fat diet-induced obese Sprague Dawley rats. Journal of Functional Foods. 9(2014): 173-182.
Chung HS et al. Ellagitannin geraniin: a review of the natural sources, biosynthesis, pharmacokinetics and biological effects. Phytochem Rev. 2017;16, 159–193.
Lestari, S. R., Djati, M. S., Rudijanto, A., & Fatchiyah, F. (2015). PPARγ expression by rambutan peel extract in obesity rat model-induced high-calorie diet. Asian Pacific Journal of Tropical Biomedicine, 5(10), 852-857.
Chung, A. P. Y., Gurtu, S., Chakravarthi, S., Moorthy, M., & Palanisamy, U. D. (2018). Geraniin protects high-fat diet-induced oxidative stress in Sprague Dawley rats. Frontiers in nutrition, 5, 17
Sukmandari NS et al. A Review on Nephelium lappaceum L. Research J. Pharm. and Tech. 10(8): August 2017

Healthy Aging

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Li Y et al. Metal Chelating, Inhibitory DNA Damage, and Anti-Inflammatory Activities of Phenolics from Rambutan (Nephelium lappaceum) Peel and the Quantifications of Geraniin and Corilagin. Molecules 2018, 23, 2263; doi:10.3390/molecules23092263
Zhuang, Y., Ma, Q., Guo, Y., & Sun, L. (2017). Protective effects of rambutan (Nephelium lappaceum) peel phenolics on H2O2-induced oxidative damages in HepG2 cells and d-galactose-induced aging mice. Food and Chemical Toxicology, 108, 554-562.
Xiao J et al. Effects of rambutan (Nephelium lappaceum) peel phenolics and Leu-Ser-Gly-Tyr-Gly-Pro on hairless mice skin photoaging induced by ultraviolet irradiation. Food and Chemical Toxicology. Volume 129, July 2019, Pages 30-37

Immune support

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Kim, Y. S., Chung, H. S., Noh, S. G., Lee, B., Chung, H. Y., & Choi, J. G. (2021). Geraniin Inhibits the Entry of SARS-CoV-2 by Blocking the Interaction between Spike Protein RBD and Human ACE2 Receptor. International Journal of Molecular Sciences, 22(16), 8604.
Abdul Ahmad, S. A., Palanisamy, U. D., Tejo, B. A., Chew, M. F., Tham, H. W., & Syed Hassan, S. (2017). Geraniin extracted from the rind of Nephelium lappaceum binds to dengue virus type-2 envelope protein and inhibits early stage of virus replication. Virology journal, 14(1), 1-13.
Sukmandari NS et al. A Review on Nephelium lappaceum L. Research J. Pharm. and Tech. 10(8): August 2017
Thitilertdecha N et al. Antioxidant and antibacterial activities of Nephelium lappaceum L. Extracts. Food Science Technology. 41:10(2008): 2029-2035

Glucose control

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Mustaffa, W. N. I. H. W., & Jusof, W. H. W. (2021). A Review on Antioxidant and Antidiabetic Activities of Nephelium Lappaceum L. Pharmacognosy Journal, 13(4).
Chigurupati S et al. Antidiabetic, antioxidant and in silico studies of bacterial endosymbiont inhabiting Nephelium lappaceum L.. Analele Universitatii «Ovidius» Constanta – Seria Chimie , Volume 30 (2): 6 – Jul 1, 2019
Muhtadi et al. Antidiabetic Activity of Durian (Durio zibethinus Murr.) and Rambutan (Nephelium lappaceum L.) Fruit Peels in Alloxan Diabetic Rats. Procedia Food Science. 3(2015 ):255–261.
Ma, Q., Guo, Y., Sun, L., & Zhuang, Y. (2017). Anti-diabetic effects of phenolic extract from rambutan peels (Nephelium lappaceum) in high-fat diet and streptozotocin-induced diabetic mice. Nutrients, 9(8), 801.
Phang, S. C. W., Palanisamy, U. D., & Kadir, K. A. (2019). Effects of geraniin (rambutan rind extract) on blood pressure and metabolic parameters in rats fed high-fat diet. Journal of integrative medicine, 17(2), 100-106.

Facilities

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As a startup, we leverage our capabilities by partnering with other companies to make this possible

We nested Rambuhealth’s novel gears in Productos Ujarrás S.A headquarters to grow together
And in order to source the market with our custom brand(Ramboost). we manufacture our supplements with the Pharmaceutical company INFARMA LTDA.
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